Archive of Louise Johnson

Bodleian Library, University of Oxford

Sean Macmillan and Emily Chen
2018



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Table of Contents

Introduction
A   Research 1914-2011
    A.1   Laboratory notebooks 1962-2009
    A.2   Laboratory of Molecular Biophysics annual progress reports 1975-2006
    A.3   Research and materials of peers and colleagues 1914-2008
    A.4   Correspondence, grants, and annotated articles 1972-2009
    A.5   Subject specific and miscellaneous research 1952-2011, n.d.
B   Administration 1965-2011
    B.1   Laboratory of Molecular Biophysics - University of Oxford 1965-2011
    B.2   Diamond Light Source 1995-2011
C   Academic visits, teaching and conferences 1997-2011
D   Publications and other scientific papers and correspondence 1934-2011
E   Organisations and consultancies 2003-2012
F   Career and personal materials 1965-2012


Archive of Louise Johnson

1914-2012

Abstract:
Archive of Louise Johnson (1940-2012), biophysicist and structural biologist.

Extent: 59 physical shelfmarks
Language(s) of Material: English

Full range of Shelfmarks:

MSS. MS. 7132/1-59

Biographical History

Biographical/historical note written with reference to Oxford DNB.

Johnson, Dame Louise Napier (1940–2012), biophysicist and structural biologist, was born 26 September 1940 in Worcester. Educated at Wimbledon High School for Girls, she went on to University College, London in 1959, obtaining a BSc (Hons) in Physics in 1962.

She carried out her doctoral research on substrate binding at the Royal Institution, London under the supervision of David Phillips, whose team was working on the structure of the enzyme lysozyme using x-ray scattering techniques. Completing her PhD thesis in 1965, her work was published in Nature and led to the first understanding--at the structural level--of the mechanism of action of an enzyme. She spent a short time at Yale University as a post-doctoral researcher under Fred Richards before returning in 1967 to join David Phillips’ newly formed Laboratory of Molecular Biophysics at Oxford University.

In Oxford, Johnson became a departmental administrator in the Zoology Department and Janet Vaughan Lecturer in Biophysics at Somerville College. In 1973 she became a university lecturer and additional fellow of Somerville College.

Realising the potential of synchrotron radiation, Johnson’s group was at the forefront of its use in the 1980s for macromolecular crystallography. Her pioneering work on glycogen phosphorylase and cell cycle regulatory proteins transformed understanding of not just large protein structures but how they worked as complex biochemical machines.

Upon Phillips’ retirement in 1990 Johnson was made the David Phillips Professor of Molecular Biophysics and took over as head of the Laboratory of Molecular Biophysics. She also became a professorial fellow of Corpus Christi College while remaining an honorary fellow of Somerville. She held these posts until her retirement in 2007.

She was elected a fellow of the Royal Society in 1990 and a member of the European Molecular Biology Organization the following year.

In 2003 she became the Life Sciences Director at Diamond Light Source; helping to lead the development of the UK’s national synchrotron and promoting its application to questions in structural biology. Her tireless work saw the establishment of the Membrane Protein Laboratory at Diamond and the Research Complex at Harwell for visiting researchers. She was made a Diamond fellow after her retirement in 2008.

On an international level Johnson supported the establishment of research laboratories in developing regions, made numerous trips to give lectures and advise scientists in developing countries and promoted projects such as the Synchrotron Light for Experimental Science and Applications in the Middle East (SESAME), which offered a unique opportunity for scientists across the Middle East to work together.

During her long career, Johnson authored or co-authored 186 peer-reviewed scientific papers as well as served on many advisory committees the world over. Her book with Tom Blundell, Protein Crystallography (1976) is considered a classic in the field and she was the recipient of numerous honours and honorary degrees. Johnson was incredibly supportive of young scientists, particularly women, and understood the challenges of juggling a scientific career with family life. She encouraged a family-friendly work ethic and cooperative working environment that trained a generation of crystallographers in Oxford. She herself married in 1968 the theoretical physicist and future Nobel laureate Muhammad Abdus Salam (1926-1996) and had a son Umar (b. 1974) and a daughter Sayyeda (b.1982). After her retirement she moved to Cambridge in 2011 to be with her son and his family. She died at Addenbrooke’s Hospital in Cambridge on 25 September 2012 and was cremated on 6 October of that year at Cambridge city crematorium.

Scope and Content

The archive consists of material relating to Louise Johnson's: A. Research, mainly in Oxford; B. Administrative roles as head of laboratory at Oxford and director of life sciences at Diamond; C. Academic visits, teaching and conferences; D. Publications and other scientific papers and correspondence; E. Organisations and consultancies; and F. Career and personal materials. This includes notebooks, personal and professional correspondence, photographs, slides, negatives, published works, printed ephemera and digital and audio visual materials.

Arrangement

No pre-existing overall arrangement was observed. The archive has therefore been arranged largely by function while emphasising original order below the series level. Where there is no discernible order files are arranged by alphabetical or chronological order where appropriate.

The archive consists of six series. The first series covers her research and that of her research group at the Laboratory of Molecular Biophysics, Oxford University; it consists of five subseries that contain laboratory notebooks, progress reports, research and other materials, correspondence (including grants and annotated articles), and miscellaneous research papers. The second series has two subseries covering Johnson's administrative papers for the Laboratory of Molecular Biophysics and Diamond Light Source, respectively. The third series covers speaking engagements and travel related to her professional life. The fourth series contains her published works and related materials; while the fifth series contains papers dealing with her work with, or consulting for, various organisations. The sixth series is arranged into three categories covering papers relating to her career, honours and recognitions received, and personal and miscellaneous materials.

Restrictions on Access

Material of a sensitive nature is closed.

Acquisition

Donated in two accessions, by Elspeth Garman, 27 February 2013, and Umar Salam, 30 August 2013.

Origination

Johnson | Louise Napier | Dame | 1940-2012

Preferred Form of Citation

Oxford, Bodleian Library [followed by shelfmark, e.g. MS. 7132/1.]

Personal name(s) (NCA Rules)

Hodgkin | Dorothy Mary Crowfoot | née Crowfoot | 1910-1994 | chemist
Phillips | Sir | David Chilton | 1924-1999 | Knight | biophysicist

Corporate name(s) (NCA Rules)

Diamond Light Source
University of Oxford | Biochemistry Department | Laboratory of Molecular Biophysics

Subject(s)

20th century
21st century
Biochemistry
Cell cycle
Crystallography
Cyclin-dependent kinases
Enzymes -- Research
Glycogen phosphorylase
Phosphorylation -- Research
Proteins -- Structure
Synchrotron radiation sources
X-ray crystallography
X-rays -- Diffraction

A   Research 1914-2011

A.1   Laboratory notebooks 1962-2009

Full range of shelfmarks:

MS. 7132/1-6

Laboratory notebooks
Date: 1962-1965, n.d.
Shelfmark: MS. 7132/1
Language(s) of Material: English
Extent: 1 box (7 volumes)

Scope and Content

Comprises:

Laboratory notebooks
Date: 1966-1975
Shelfmark: MS. 7132/2
Language(s) of Material: English
Extent: 1 box (5 volumes)

Scope and Content

Comprises:

Laboratory notebooks
Date: 1979-1991
Shelfmark: MS. 7132/3
Language(s) of Material: English
Extent: 1 box (7 volumes)

Scope and Content

Comprises:

Laboratory notebooks
Date: 1989-2002
Shelfmark: MS. 7132/4
Language(s) of Material: English
Extent: 1 box (6 volumes)

Scope and Content

Comprises:

Laboratory notebooks
Date: 2002-2007
Shelfmark: MS. 7132/5
Language(s) of Material: English
Extent: 1 box (5 volumes)

Scope and Content

Comprises:

Laboratory notebooks
Date: 2005-2009
Shelfmark: MS. 7132/6
Language(s) of Material: English
Extent: 1 box (4 volumes)

Scope and Content

Comprises:

A.2   Laboratory of Molecular Biophysics annual progress reports 1975-2006

Full range of shelfmarks:

MS. 7132/7-9

Annual progress reports
Date: 1975-1984
Shelfmark: MS. 7132/7
Language(s) of Material: English
Extent: 1 box (10 volumes)

Scope and Content

Comprises:

Annual progress reports
Date: 1985-1993
Shelfmark: MS. 7132/8
Language(s) of Material: English
Extent: 1 box (8 volumes)

Scope and Content

Comprises:

Annual progress reports
Date: 1994-2006
Shelfmark: MS. 7132/9
Language(s) of Material: English
Extent: 1 box (12 volumes)

Scope and Content

Comprises:

A.3   Research and materials of peers and colleagues 1914-2008

Full range of shelfmarks:

MS. 7132/10-13

Research and papers of peers and colleagues
Date: 1914-2008
Shelfmark: MS. 7132/10
Language(s) of Material: English
Extent: 1 box (6 folders)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed


Research and papers of peers and colleagues
Date: 1953-2007
Shelfmark: MS. 7132/11
Language(s) of Material: English
Extent: 1 box (5 folders)

Scope and Content

Comprises:

Research and papers of peers and colleagues
Date: 1967-2007
Shelfmark: MS. 7132/12
Language(s) of Material: English
Extent: 1 box (3 folders)

Scope and Content

Comprises:

Research and papers of peers and colleagues
Date: 1939-2007
Shelfmark: MS. 7132/13
Language(s) of Material: English
Extent: 1 box (5 folders)

Scope and Content

Comprises:

A.4   Correspondence, grants, and annotated articles 1972-2009

Full range of shelfmarks:

MS. 7132/14-17

Correspondence and grant applications to the Medical Research Council (MRC)
Date: 1972-2007
Shelfmark: MS. 7132/14
Language(s) of Material: English
Extent: 1 box (5 folders)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed


Grant applications to the Medical Research Council (MRC)
Date: 1990-2009
Shelfmark: MS. 7132/15
Language(s) of Material: English
Extent: 1 box (6 folders)

Scope and Content

Comprises:

Restrictions on Access:

Closed


Grant applications to the Medical Research Council (MRC) and Wellcome Trust
Date: 2000-2009
Shelfmark: MS. 7132/16
Language(s) of Material: English
Extent: 1 box (5 folders)

Scope and Content

Comprises:

Restrictions on Access:

Closed


Annotated articles
Date: 1974-2008
Shelfmark: MS. 7132/17
Language(s) of Material: English
Extent: 1 box (4 folders)

Scope and Content

Comprises:

A.5   Subject specific and miscellaneous research 1952-2011, n.d.

Full range of shelfmarks:

MS. 7132/18-28

Papers relating to cdk 9, flavopiridol, PLK, and other related subjects
Date: 2002-2010
Shelfmark: MS. 7132/18
Language(s) of Material: English
Extent: 1 box (3 folders)

Scope and Content

Comprises:

Papers concerning protein kinases, X-ray diffraction and other related subjects
Date: 1948-2011
Shelfmark: MS. 7132/19
Language(s) of Material: English
Extent: 1 box (4 folders)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed


X-ray diffractions
Date: 1979-1981
Shelfmark: MS. 7132/20
Language(s) of Material: English
Extent: 1 box

Scope and Content

X-ray diffraction photographs titled 'Glycogen Phosphorylase b G7 + pi collected at Desy', 27 Nov 1979-Feb 1981

Materials relating to protein structures and miscellaneous biochemical subjects
Date: 1963-2001
Shelfmark: MS. 7132/21
Language(s) of Material: English
Extent: 1 box

Scope and Content

Comprises:

16mm films relating to lysozyme activity
Date: n.d. circa 1975
Shelfmark: MS. 7132/22
Language(s) of Material: English
Extent: 1 box

Scope and Content

Comprises:

Restrictions on Access:

Closed


16mm film - 'The Structure Hen Egg White Lysezym B/A silent print'
Date: 1975
Shelfmark: MS. 7132/23
Language(s) of Material: English
Extent: 1 box

Restrictions on Access:

Closed


16mm film - 'The Lysozyme molecule'
Date: n.d. circa 1975
Shelfmark: MS. 7132/24
Language(s) of Material: English
Extent: 1 box

Restrictions on Access:

Closed


16mm film - 'Lysozyme molecule' (Prof D.C. Phillips)'
Date: n.d. circa 1975
Shelfmark: MS. 7132/25
Language(s) of Material: English
Extent: 1 box

Restrictions on Access:

Closed


16mm film - 'Lights Lys[ozyme]'
Date: n.d. circa 1975
Shelfmark: MS. 7132/26
Language(s) of Material: English
Extent: 1 box

Restrictions on Access:

Closed


VHS cassette - 'Catalysis by phosphorylase B, produced by S.E.R.C Dresbury Laboratory Department', n.d.
Date: n.d. circa 1980
Shelfmark: MS. 7132/27
Language(s) of Material: English
Extent: 1 box

Restrictions on Access:

Closed


16mm film - 'PPB film, Mar 1986'
Date: 1986
Shelfmark: MS. 7132/28
Language(s) of Material: English
Extent: 1 box

Restrictions on Access:

Closed


B   Administration 1965-2011

B.1   Laboratory of Molecular Biophysics - University of Oxford 1965-2011

Full range of shelfmarks:

MS. 7132/29-38

General administration and funding
Date: 1964-2011, n.d.
Shelfmark: MS. 7132/29
Language(s) of Material: English
Extent: 1 box (8 folders)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed


General administration and funding
Date: 1967-2009, n.d.
Shelfmark: MS. 7132/30
Language(s) of Material: English
Extent: 1 box (5 folders)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed


General administration and funding
Date: 2002-2008
Shelfmark: MS. 7132/31
Language(s) of Material: English
Extent: 1 box (4 files)

Scope and Content

Comprises:

Departmental lectures, seminars and presentations
Date: 1995-2010
Shelfmark: MS. 7132/32
Language(s) of Material: English
Extent: 1 box (6 folders)

Scope and Content

Comprises:

Departmental lectures, seminars and presentations
Date: 2002-2008
Shelfmark: MS. 7132/33
Language(s) of Material: English
Extent: 1 box (4 files)

Scope and Content

Comprises:

Departmental lectures, seminars and presentations
Date: 1965-1999
Shelfmark: MS. 7132/34
Language(s) of Material: English
Extent: 1 box (4 files)

Scope and Content

Comprises:

Staff and student recruitment and evaluation
Date: 1989-2010
Shelfmark: MS. 7132/35
Language(s) of Material: English
Extent: 1 box (8 folders)

Scope and Content

Comprises:

Restrictions on Access:

Closed


Staff and student recruitment and evaluation
Date: 1987-2010
Shelfmark: MS. 7132/36
Language(s) of Material: English
Extent: 1 box (3 folders)

Scope and Content

Comprises:

Restrictions on Access:

Closed


Staff and student recruitment and evaluation
Date: 1992-2010
Shelfmark: MS. 7132/37
Language(s) of Material: English
Extent: 1 box (3 folders)

Scope and Content

Comprises:

Restrictions on Access:

Closed


Departmental administration and scientific correspondence
Date: 1999-2011
Shelfmark: MS. 7132/38
Language(s) of Material: English
Extent: 1 box (3 folders)

Scope and Content

Comprises:

Restrictions on Access:

Closed


B.2   Diamond Light Source 1995-2011

Full range of shelfmarks:

MS. 7132/39-46

General administration and funding applications
Date: 2001-2010
Shelfmark: MS. 7132/39
Language(s) of Material: English
Extent: 1 box (3 folders)

Scope and Content

Comprises:

General administration and funding applications
Date: 2003-2010
Shelfmark: MS. 7132/40
Language(s) of Material: English
Extent: 1 box (4 files)

Scope and Content

Comprises:

Lectures, seminars and presentations
Date: 2005-2011
Shelfmark: MS. 7132/41
Language(s) of Material: English
Extent: 1 box (3 files)

Scope and Content

Comprises:

Project planning and construction
Date: 1997-2009
Shelfmark: MS. 7132/42
Language(s) of Material: English
Extent: 1 box (5 folders)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed


Project planning and construction
Date: 2005-2010
Shelfmark: MS. 7132/43
Language(s) of Material: English
Extent: 1 box (7 files)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed


Project planning and construction
Date: Bulk, 2009-2010 1982-2010 mainly 2009-2010
Shelfmark: MS. 7132/44
Language(s) of Material: English
Extent: 1 box (3 folders)

Scope and Content

Comprises:

Staff recruitment and evaluation
Date: 1995-2011
Shelfmark: MS. 7132/45
Language(s) of Material: English
Extent: 1 box (4 folders)

Scope and Content

Comprises:

Restrictions on Access:

Closed


Related professional and scientific papers and correspondence
Date: 2003-2011
Shelfmark: MS. 7132/46
Language(s) of Material: English
Extent: 1 box (3 folders)

Scope and Content

Comprises:

Restrictions on Access:

Partially closed


C   Academic visits, teaching and conferences 1997-2011

Full range of shelfmarks:

MS. 7132/47-49


Memorial and other invited lectures
Date: 2000-2011
Shelfmark: MS. 7132/47
Language(s) of Material: English
Extent: 1 box (2 folders)

Scope and Content

Comprises:

Meetings and visits
Date: 1997-2011
Shelfmark: MS. 7132/48
Language(s) of Material: English
Extent: 1 box (5 folders)

Scope and Content

Comprises:

Meetings and visits
Date: 2010-2011
Shelfmark: MS. 7132/49
Language(s) of Material: English
Extent: 1 box

Scope and Content

Comprises:

D   Publications and other scientific papers and correspondence 1934-2011

Full range of shelfmarks:

MS. 7132/50-53


Published works, peer reviews and external examinations
Date: 2002-2011
Shelfmark: MS. 7132/50
Language(s) of Material: English
Extent: 1 box (3 folders)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed


Hodgkins, Dorothy: scientific papers and correspondence
Date: 1934-2010
Shelfmark: MS. 7132/51
Language(s) of Material: English
Extent: 1 box (4 folders)

Scope and Content

Comprises:

Phillips, David: scientific papers and correspondence
Date: 1971-2000
Shelfmark: MS. 7132/52
Language(s) of Material: English
Extent: 1 box (2 folders)

Scope and Content

Comprises:

Phillips, David: scientific papers and correspondence
Date: 1969-2001
Shelfmark: MS. 7132/53
Language(s) of Material: English
Extent: 1 box (3 folders)

Scope and Content

E   Organisations and consultancies 2003-2012

Full range of shelfmarks:

MS. 7132/54-56


Organisations and consultancies
Date: 2003-2011
Shelfmark: MS. 7132/54
Language(s) of Material: English
Extent: 1 box (6 folders)

Scope and Content

Comprises:

Restrictions on Access:

Closed


Organisations and consultancies
Date: 2004-2011
Shelfmark: MS. 7132/55
Language(s) of Material: English
Extent: 1 box (5 folders)

Scope and Content

Comprises:

Restrictions on Access:

Closed


Organisations and consultancies
Date: 2009-2012
Shelfmark: MS. 7132/56
Language(s) of Material: English
Extent: 1 box (2 folders)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed


F   Career and personal materials 1965-2012

Full range of shelfmarks:

MS. 7132/57-59


Correspondence and papers pertaining to Louise Johnson's career activities
Date: 1965-2011
Shelfmark: MS. 7132/57
Language(s) of Material: English
Extent: 1 box (7 folders)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed


Correspondence and papers pertaining to Louise Johnson being honoured and professionally recognised
Date: 1989-2010
Shelfmark: MS. 7132/58
Language(s) of Material: English
Extent: 1 box (6 folders)

Scope and Content

Comprises:

Correspondence and papers pertaining to Louise Johnson being honoured and professionally recognised, in addition to miscellaneous personal materials
Date: circa 1958-2012
Shelfmark: MS. 7132/59
Language(s) of Material: English
Extent: 1 box (7 folders)

Scope and Content

Comprises:

Restrictions on Access:

Some material is closed



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